This page covers the ingredients found in Lean Optimizer™ and discusses WHY they work, including links to clinical and scientific studies. The top portion of this page will cover the "Supplement Facts" (ingredients, servings per bottle, dosages, etc.). You'll have a quick overview of proven formula.

The bottom portion of this page will list all the specific ingredients and a short overview about their benefits, pros and cons. Then you'll know how weight management and fat loss is so much easier when you're utilizing Lean Optimizer™ and why it's better than other solutions on the market.

Supplement Facts
Serving Size: 3 Capsules
Servings Per Container: 30

Amount Per Serving
%Daily Value

1500 MCG
Iodine (Potassium Iodide)
760 MCG
Chromium Picolinate
450 MCG
60 MG
Thyroid Optimizer™
120 MG
Guggulsterones (std. 10% extract, E + Z 1:1)
Cortisol Minimizer™
350 MG
Sensoril® Ashwagandha extract (32% oligosaccharides, 10% withanolide)
7-Keto® DHEA
Appetite Minimizer™
260 MG
Coleus forskholii
Metabolic / Thermogenic Optimizer™
155 MG
Citrus Aurantium (Bitter Orange, p-Synephrine)
Capsimax® (Capsicum Extract Beadlets (2% Capsaicinoids))
Paradoxine® (Grains of Paradise 15%)
Leptin Optimizer™
250 MG
African Mango 10:1 (Irvingia Gabonensis)
Fat Cell Minimizer™
550 MG
Green Tea Extract (95% Polyphenols., 45% EGCG.,< 6% Caffeine)
Ghrelin & Adiponectin Optimizer™
450 MG
Estrogen Minimizer™
100 MG
White Button Mushroom Extract 10:1 (Agaricus bisporus)
Insulin Minimizer™
450 MCG
Chromium Picolinate

† Daily Value not established
* Percent Daily Values are based on a 2,000 calorie diet.
Made in USA Gluten free Vegetarian Non GMO Additive and filler free
Recommended Use: If you are NEW to this dietary supplement, please begin your first week (7 days) by taking 1 pill in the morning, prior to breakfast and 1 pill 4-6 hours later. Beginning your SECOND week, you should increase the dosage to 2 pills, twice daily for a total of 4 pills daily. If additional fat loss is desired, you can take 2 pills, 3x daily for a total of 6 pills daily.

It's best to take the pills on an empty stomach, about 15 minutes before a meal with 2 cups of water.

For best results, combine with a reduced calorie diet and exercise program. Use continuously for a minimum of 6-8 weeks to optimally promote your fat-burning metabolism. If you have trouble sleeping, do not take within 6 hours of bedtime.

Other Ingredients: plant-derived cellulose gelatin (Vegetarian capsule), Rice Flour

Does NOT Contain Any: Artificial colors, wheat, gluten, soy, dairy, egg, fish, peanuts.

Side Effects: There are no known side-effects associated with this formula. However, as with any food product, there may be infrequent and highly sensitized reactions associated with this or any other nutritional supplement. If such a reaction occurs, you should consider discontinuing use of this or any product.

Warnings & Interactions: Do not use if you are pregnant, may become pregnant or are nursing. As with any new supplement, you may want to consult with your doctor prior to use. Keep tightly closed, in a cool dry place and away from children.

Sensoril® is protected under US Patent Nos. 6,153,198 and 6,713,092 and is a registered trademark of Natreon, Inc.
LOWAT® is a trademark exclusively distributed by InterHealth N.I.

Get The Facts:

Below you'll find detailed descriptions about the ingredients utilized in Lean Optimizer™ - exactly HOW it works & WHY it's better than other products. To get started, simply click on the descriptions below and a detailed overview and summary will appear under it.

However, if you're in a rush and want a quick overview, Lean Optimizer™ was designed to help promote and support:

  • Thyroid Optimizer™

    Pre Summary

    One of the reasons for a slower metabolism is lower production of thyroid hormones (T4, T3 and T3). Now, even though a person may do a hormone test showing "normal" levels of thyroid hormones, it does NOT mean they are at OPTIMAL levels. And sadly, as we get older, thyroid production decreases. Poor sleep, stress, higher estrogen, soy, certain drugs, dieting and lower carbohydrate diets also further decrease thyroid production. Women are affected by this more than men. The below ingredients help optimize your thyroid production, which can help increase your metabolism, burn fat and improve carbohydrate utilization.

    Overview of Ingredients

    Guggulsterones (std. 10% extract, E + Z 1:1) Helps increase and support the activity of the enzyme that converts T4 into the most active thyroid hormone, T3... helping to increase your metabolism and fat burning.1

    Iodine is an element that is needed for the production of thyroid hormone. The body does not make iodine, so it is an essential part of your diet. Unfortunately, iodine deficiency has increased more than fourfold over the past 40 years. Nearly 84% of normal, “healthy” adults may no longer consume enough iodine.2,3

  • Cortisol Minimizer™

    Pre Summary

    One of main problems with today's modern life-styles is higher levels of stress. Our brains work more, we sleep less and we work longer hours... all the time being pulled in many different directions and getting bombarded with information all day long. This causes a dramatic increase in stress hormones such as cortisol, which is known to increase belly fat. Additionally, elevated stress hormones cause higher blood sugar levels, which further cause weight gain. Lastly, higher cortisol levels cause an imbalance and a decrease in positive, "youth" hormones such as testosterone and growth hormones. The following ingredients have been clinically shown to help reduce elevated cortisol levels:

    Overview of Ingredients

    Sensoril® Ashwagandha extract (32% oligosaccharides, 10% withanolide) counters the oxidative damage generated by nervous tension and physical stress.5,10-11 In a large clinical trial, Ashwagandha reduced levels of the stress hormone cortisol by up to 26% while maintaining healthy blood sugar levels and lipid profiles.,7,10-12 Subjects reported improvements in energy, sleep and well-being, as well as diminished fatigue.4 Additional benefits help support natural production of thyroid hormones for a faster metabolism.10 Lastly, Ashwagandha can help improve a sense of well-being and a healthy outlook.5-7

    NOTE: Sensoril® is the only patented version of Ashwagandha extract that has 12 HUMAN clinical studies showing effectiveness and potency, Standardized to 3 bioactives (Withanolide glycosides, Withaferin A, Oligosaccharides).13

    7-Keto® DHEA is not a hormone, such as DHEA. However, it does interact with the stress hormone, Cortisol – by reducing it, which can lead to a decrease in belly fat, sugar cravings and blood sugar levels. 7-Keto® DHEA also helps increase metabolic rate, which increases caloric expenditure, leading to faster fat loss.14 It can also help increase the active thyroid hormone, T3 – leading to a faster metabolism.15

    NOTE: There are different forms and brands of 7-Keto DHEA. However, we utilize the 7-Keto® brand. This is patented and has 4 human, published clinically studies which has demonstrated to help maintain metabolic rate and increase weight loss 2.9x more than diet and exercise alone.16 In another clinical study, 7-Keto® was shown to decrease weight by 6.35 pounds after 8 weeks.16

  • Appetite Minimizer™

    Pre Summary

    One big reason for gaining weight is an increase in appetite, especially due to "cravings" for sugary, carbohydrate foods. During times of stress (physical, emotional, lack of sleep), cortisol levels go up and serotonin levels go down, causing an increase in appetite and cravings. This especially happens to women when pre menstraul. Some people are also known to be "stress eaters". Will-Power can only go so far and thus, decreasing your appetite is a must for long-term weight loss.

    Overview of Ingredients

    5-HTP is an amino acid that aids in the production of the “brain chemical”, serotonin. The lower your serotonin levels are, the more likely you are to over eat even when you’re not hungry.19 On the flip side, higher serotonin levels have been associated with a decrease in cravings and increased satiety, which is the the sensation of feeling “full” after a meal.19 Studies have shown that subjects taking 5-HTP (with no other changes) effortlessly lost over 4.5 pounds in 5 weeks, simply due to the increased sense of satiety.20,21

    Theobromine contains natural substances that reduce hunger and suppress your appetite, which can lead to weight loss.17 Another benefit is that it helps increase energy levels, which induces further weight loss. Clinical studies also demonstrate that it helps break down “stubborn” fat.18

    Coleus forskholii (10% forskolin) helps reduce appetite and lowers blood sugar levels.23 In one study, users saw a decrease in body fat percentage, while actually seeing an increase in lean muscle mass.24 Positive effects are also seen and felt in both men and women.24 In another study, subjects showed an average of 10 lbs of weight loss within an eight-week period.24

  • Metabolic / Thermogenic Optimizer™

    Pre Summary

    Anything that will increase your metabolism and turn UP your body temperature ("thermogenic"), will cause weight loss and more specifically, FAT loss. Unfortunately, aging causes a decrease in your metabolism and so does dieting and stress. The below clinically validated ingredients will help reverse this and help turn on your "fat burning" hormones:

    Overview of Ingredients

    Citrus Aurantium/Advantra Z® (Bitter Orange, p-Synephrine) - studies show that this herbal extract speeds up your metabolism, which contributes to fat loss and weight management.30 It increases energy expenditure, leading to faster weight loss.30 Research also shows that it can increase the thermic effect of food, especially in women. This means even more energy expenditure and thus, more fat loss.31 Another benefit is that synephrine can aid in mobilizing stubborn fat cells by blocking the activity of alpha-receptors in fat cells.32 This means easier and faster FAT loss, especially the “stubborn” areas like stomach, “love handles”, thighs and butt.

    NOTE: Advantra Z® is the only form Citrus aurantium that's patented specifically for weight loss and physical performance in North America. It has 4 patents for
    • stimulating thermogenesis (increase body temperature)
    • reducing weight
    • increasing lean muscle mass to total body mass
    • improving athletic performance
    • suppressing appetite

    Capsimax® (Capsicum Extract Beadlets (2% Capsaicinoids)) was shown in a clinical study to help boost users’ metabolism, demonstrating great potential for “long-term weight management”. Additional studies have also shown, anti-inflammatory, antioxidant, and even anti-cancer benefits, in addition to potentially decreasing the chance of obesity.25,27

    NOTE:The patented form of Capsimax®, is the ONLY type of "capsicum extract" that's supported by multiple studies with findings showing safety, increased lipolysis and satiety, and improved healthy body composition.26,27

    Paradoxine® (Grains of Paradise 15%) There are certain, genetically gifted people who actually burn fat, when they eat. It’s called, “diet-induced thermogenesis”. In humans, there are two types of fat (adipose tissue), WAT (white adipose tissues) and BAT (brown adipose tissues). WAT is the sites of energy storage, while BAT is responsible for cold-and diet-induced thermogenesis, which helps to control body-energy expenditure, as well as body fat content. Simply stated, people who have more WAT, tend to store food as body fat more easily, than those who have more BAT, which actually burns fat and causes weight loss.

    Paradise extract (especially including 12.5% 6-paradol from clinically tested and patented Paradoxine®) was found to promote WAT transformation into BAT.28,29 This means you can actually help "enhance" your genetics to have more of the “thermogenic, fat BURNING” brown fat, than the unwanted, “fat storing” white fat.

  • Leptin Optimizer™

    Pre Summary

    Leptin is what scientist call the "Master" hormone that regulates body weight. In fact, being resistant to this hormone's effects (called Leptin resistance) is now believed to be the leading driver of fat gain in humans.37 Leptin is a hormone that is produced by the body's fat cells and it is often referred to as the "satiety hormone" or the "starvation hormone." The Leptin system evolved to keep us from starving or overeating, both of which would have made us less likely to survive in the natural environment.

    Unfortunately these days, Leptin is very effective at keeping us from starving and many people have become "Leptin Resistant", which is causing people to keep eating, even when they are NOT hungry anymore or we need to stop gaining weight. Thus, your goal is to reverse "Leptin resistance", become more sensitive to this hormone, which will turn OFF your appetite and prevent you from eating excess food and gaining extra fat.

    Overview of Ingredients

    African Mango (10:1 Extract; Irvingia Gabonensis) can suppress fat production by 34,35:

    • Reducing the activity of the protein "PPARγ", which promotes weight gain
    • Increasing adiponectin, a protein hormone involved in fat breakdown and glucose control
    • Reversing Leptin resistance, a factor that can lead to obesity. By improving/increasing Leptin levels, you can dramatically reduce your appetite and cravings.

    In a 10-week study of 120 overweight volunteers, African mango supplements significantly reduced weight, body fat (6.3% avg.) and waistline circumference (16.2% avg.) 36.

    Similar effects were seen in a 4-week study of 140 obese subjects. In this study, the African mango treated group showed an average decrease in body weight and LDL (“bad”) cholesterol levels as well as an increase in HDL (“good”) cholesterol levels.39 Another study of 72 patients found that it significantly decreased body weight, body fat (20.1%) and waistline circumference compared to placebo after 10 weeks.40

  • Fat Cell Minimizer™

    Pre Summary

    One of the problems with getting fatter is not only do your fat cells grow in size, but they can actually split, replicate and multiply! Yup, this means you actually change your genes and gain MORE fat cells than you were born with. Which means that it's extremely difficult to decrease the fat cells (but you can always shrink them) and lose weight.

    Sadly, you can't do that with muscle cells. You have what your born with and that's the limiting factor. Yet, there's NO limit to how many NEW fat cells you can grow. The good news is that there are herbs which actually help reduce, limit and even prevent new fat cells from being produced.

    Overview of Ingredients

    Meratrim® was developed by researchers who discovered that when two natural herbs combined together [Sphaeranthus indicus (a flower) and Garcinia mangostana (a fruit)], in a specific 3:1 ratio, helped 38:

    • Make it harder for fat cells to multiply
    • Decrease the amount of fat that fat cells pick up from the bloodstream
    • Help fat cells burn stored fat

    A 16-week study41 showed participants who used Meratrim, in place of the placebo, lost on average 11 lbs, 4.9 inches off their waist and 4.1 inches from their hips. A second 8-week study42 support these results as Meratrim participants lost 8.25 lbs and 2.14 inches in weight and waist circumference, respectively.

    Green Tea Extract (95% Polyphenols., 45% EGCG.,< 6% Caffeine) Compounds in green tea (polyphenols and especially, EGCG) increase levels of hormones (such as norepinephrine) that tell fat cells to break down fat. This releases fat into the bloodstream and makes it available as energy, resulting in fat loss.43,44 Another benefit with green tea extract is that it helps your body burn more calories, even when doing nothing and resting. Studies show from 4% to 10% more calories.45-47 For a standard 2000 calorie day, that's an extra 80-200 extra calories burned, without any change in diet or exercise.

  • Ghrelin & Adiponectin Optimizer™

    Pre Summary

    Genetics aside, hormones really do control almost everything in your body. Two of the most powerful "weight loss" hormones are Adiponectin and Ghrelin. Adiponectin is the hormone that makes your fat cells burn fat for energy. And Ghrelin is the hormone responsible for making you hungry. The research is clear on both adiponectin and ghrelin: Increasing adiponectin and decreasing ghrelin leads to less body fat, faster weight loss and a decrease in cravings and appetite.

    Overview of Ingredients

    LOWAT® is a proprietary weight-loss blend that is supported by a peer-reviewed, published, randomized, double-blind, placebo-controlled study. This unique Ayurvedic blend of Piper betle leaf & Dolichos biflorus seed extracts has a unique mechanism which supports weight loss and decrease BMI 2.4x more than placebo with an average 9.4 pound weight loss after 8 weeks.57-60

    Additionally, LOWAT® significantly decreased the hunger-inducing hormone, ghrelin, by 17.3% -- resulting in a reduced appetite. Plus, it helps increase adiponectin, the hormone that makes your fat cells burn fat for energy.57-60

  • Estrogen Optimizer™

    Pre Summary

    Both men and women produce estrogen, the "female" hormone -- but women produce much higher levels. Unfortunately, one of the effects of estrogen is an increase in body fat and this is why women have more difficult losing weight. As men age, their estrogen levels increase, which also causes a decrease in testosterone -- both resulting in higher body fat. As your body fat increases, so does your estrogen levels even further because fat cells produce additional estrogen, thus making it even harder to lose fat. Lastly, there are a lot of environmental estrogens that further increase estrogen levels, above what your body should have, naturally. However, your goal is not to have "low" estrogen, because it has many benefits. Instead, you want to lower excess levels and optimize them naturally, to prevent body fat and speed up fat loss.

    Overview of Ingredients

    White Button Mushroom (Extract 10:1 Agaricus bisporus) has been shown to lower excess estrogen by acting as an “aromatase inhibitor”.48,49 It does not cause "low" estrogen, but simply lowers "high" estrogen and external, environmental estrogens -- which is unnatural to the body.

  • Insulin Minimizer™

    Pre Summary

    Every time you eat, your pancreas produces insulin - the hormone that helps lower blood sugar to healthy levels. It takes the foods you eat (carbs and proteins), into your cells and uses it for energy and repair. Unfortunately, as you age and/or gain weight, your body becomes "insulin resistant". This means your body now produces even MORE insulin to lower blood sugar, which then causes the glucose (from your food) to be stored as body fat. This will cause more weight gain and eventually, to diabetes.

    Overview of Ingredients

    Chromium Picolinate - More than 90% of U.S. adults have a deficiency in chromium because it is not readily absorbed from foods, and the human body even has difficulty in absorbing chromium from most nutritional supplements. Because of this, there are dozens and hundreds of clinical studies about Chromium as it relates to improvements in blood glucose, insulin and HbaA1c levels... An increase in insulin sensitivity, appetite reduction, a decrease in fat mass, accelerated weight loss, and more.50-56 Simply stated, chromium helps enhance the effectiveness of insulin, a hormone vital for the processing of glucose and preventing weight gain, especially belly fat.

Ingredient References: